Santee is the principal village of the Santee Sioux Reservation in Knox County, Nebraska, United States. Landmarks include Church of Our Most Merciful Saviour and Congregational Church and Manse.
- CountySantee Sioux Indian Reservation
- Population424 (2020 U.S. Census)
- Historic places2 on the National Register


























Church of Our Most Merciful Saviour
Congregational Church and Manse
A view of Santee
A view of Santee