Paynesville is a village in Pike County, Missouri, United States. Landmarks include Meloan, Cummins & Co., General Store. Paynesville is the birthplace of Paul Meloan, Major League Baseball outfielder.
- CountyPike County
- Population60 (2020 U.S. Census)
- Historic places1 on the National Register




















Meloan, Cummins & Co., General Store