Although the current Town of Mayo was settled and established in 1874 by John B. Whitfield, the town was not officially incorporated as a municipality until 1903. Landmarks include House of the Seven Gables, M. Pico Building and Old Mayo Free Press Building. Mayo is the birthplace of Reggie McGrew, college football player, professional football player, defensive lineman, defensive tackle.
- CountyLafayette County
- Population1,055 (2020 U.S. Census)



































Lafayette County Courthouse
Old Lafayette County Courthouse
Dee's Drug Store
Veterans Memorial Park of Mayo